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Molecular Interaction Guides Neurons in Developing Brain

This journal cover design highlights the findings of a research by the Seiradake Lab: three molecules (Teneurin-Latrophilin-FLRT, foreground) interact between radial glial cells and neurons (green and blue, background) in the developing brain to ensure the neurons migrate correctly. The bright region where the molecules interact is better understood than the darker regions.

Publication: Del Toro D, Carrasquero-Ordaz MA, Chu A, et al. Structural Basis of Teneurin-Latrophilin Interaction in Repulsive Guidance of Migrating Neurons. Cell. 2019 Dec 31

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