All 2D 3D Animation Cellular and Molecular Journal Covers Mechanism of Action Publications SARSCoV2_4ways_FalconieriVisuals-01 Coronavirus Virion Style Variants astrocyte-potassium Astrocyte Potassium Spatial Buffering Falconieri_Convergent-01 Convergent Therapeutics Jan 26 2022-watermark Antibody to neutralize diverse coronaviruses Omicron spike protein mutations Close up view of SARS-CoV-2 spike protein. Areas affected by Omicron mutations that evade antibodies are highlighted in red. Omicron’s mutations visualized FalconieriHays_AwardofExcellence_DeltasDefiningMutations04 Delta’s defining mutations Inflammasome assembly Molecular subunits of the inflammasome coalesce into the 11-fold symmetric disk that forms the active signalling assembly NLRP3 Inflammasome Assembly Lipid Nanoparticle with circRNA Lipid nanoparticle with circular mRNA (oRNA, yellow), PEG lipids (light blue), phospholipid (magenta), ionizable lipid (blue), and cholesterol (purple). Lipid Nanoparticle orna-therapeutics-animation Orna Therapeutics Splash Animation Transcription by RNA Polymerase II RNA polymerase transcribes an mRNA strand from a DNA template RNA polymerase II transcribes mRNA Umoja In vivo targeted CAR-T immuntherapy Umoja Biopharma Splash Illustration BCL6 filament Targeted protein degradation is a powerful potential therapeutic approach. Here, cancer-related protein BCL6 is bound by a novel small molecule inhibitor (blue) that causes filament formation and subsequent degradation. Small Molecule Induced Polymerization and Degradation of BCL6 SARs-CoV-2 virus Coronavirus SARS-CoV-2 in 3D IgA Attacks Virus Immunoglobulin A (IgA) molecule binds between two viruses in the lumen of the intestine Immunoglobulin A (IgA) Attacks Virus FalconieriHays_LopesNatureMaterialsCover_AsPrinted Platinum-Gold Catalyst, Nature Materials Journal Cover Supercharging messenger RNA Supercharged mRNA is translated by a ribosome. Unmodified mRNA is degraded by a red protein. Cell nucleus and organelles in the background Super charging messenger RNA Load More Loading More… You’ve reached the end of the list
Omicron spike protein mutations Close up view of SARS-CoV-2 spike protein. Areas affected by Omicron mutations that evade antibodies are highlighted in red. Omicron’s mutations visualized
Inflammasome assembly Molecular subunits of the inflammasome coalesce into the 11-fold symmetric disk that forms the active signalling assembly NLRP3 Inflammasome Assembly
Lipid Nanoparticle with circRNA Lipid nanoparticle with circular mRNA (oRNA, yellow), PEG lipids (light blue), phospholipid (magenta), ionizable lipid (blue), and cholesterol (purple). Lipid Nanoparticle
Transcription by RNA Polymerase II RNA polymerase transcribes an mRNA strand from a DNA template RNA polymerase II transcribes mRNA
BCL6 filament Targeted protein degradation is a powerful potential therapeutic approach. Here, cancer-related protein BCL6 is bound by a novel small molecule inhibitor (blue) that causes filament formation and subsequent degradation. Small Molecule Induced Polymerization and Degradation of BCL6
IgA Attacks Virus Immunoglobulin A (IgA) molecule binds between two viruses in the lumen of the intestine Immunoglobulin A (IgA) Attacks Virus
FalconieriHays_LopesNatureMaterialsCover_AsPrinted Platinum-Gold Catalyst, Nature Materials Journal Cover
Supercharging messenger RNA Supercharged mRNA is translated by a ribosome. Unmodified mRNA is degraded by a red protein. Cell nucleus and organelles in the background Super charging messenger RNA