Portfolio Tag: Mechanism of action Back to Portfolio All 2D 3D Animation Cellular and Molecular Journal Covers Mechanism of Action Publications Omicron spike protein mutations Close up view of SARS-CoV-2 spike protein. Areas affected by Omicron mutations that evade antibodies are highlighted in red. 2D Omicron’s mutations visualized Inflammasome assembly Molecular subunits of the inflammasome coalesce into the 11-fold symmetric disk that forms the active signalling assembly 3D NLRP3 Inflammasome Assembly Lipid Nanoparticle with circRNA Lipid nanoparticle with circular mRNA (oRNA, yellow), PEG lipids (light blue), phospholipid (magenta), ionizable lipid (blue), and cholesterol (purple). 3D Lipid Nanoparticle Transcription by RNA Polymerase II RNA polymerase transcribes an mRNA strand from a DNA template 3D RNA polymerase II transcribes mRNA Umoja In vivo targeted CAR-T immuntherapy 3D Umoja Biopharma Splash Illustration BCL6 filament Targeted protein degradation is a powerful potential therapeutic approach. Here, cancer-related protein BCL6 is bound by a novel small molecule inhibitor (blue) that causes filament formation and subsequent degradation. 3D Small Molecule Induced Polymerization and Degradation of BCL6 1 2 3
Omicron spike protein mutations Close up view of SARS-CoV-2 spike protein. Areas affected by Omicron mutations that evade antibodies are highlighted in red. 2D Omicron’s mutations visualized
Inflammasome assembly Molecular subunits of the inflammasome coalesce into the 11-fold symmetric disk that forms the active signalling assembly 3D NLRP3 Inflammasome Assembly
Lipid Nanoparticle with circRNA Lipid nanoparticle with circular mRNA (oRNA, yellow), PEG lipids (light blue), phospholipid (magenta), ionizable lipid (blue), and cholesterol (purple). 3D Lipid Nanoparticle
Transcription by RNA Polymerase II RNA polymerase transcribes an mRNA strand from a DNA template 3D RNA polymerase II transcribes mRNA
BCL6 filament Targeted protein degradation is a powerful potential therapeutic approach. Here, cancer-related protein BCL6 is bound by a novel small molecule inhibitor (blue) that causes filament formation and subsequent degradation. 3D Small Molecule Induced Polymerization and Degradation of BCL6
